High school is like a community, where you know everyone in the whole class. Even if you are not a friend of all of them, at least you know their names. In college, you would be lucky if you find a familiar face or make a friend in the entire lecture room. Sometimes you will see strangers sitting beside you, who will be missing until exams.
You might not always be appreciated for playing a musical instrument or having some talent in co-curricular activities. That is not the way things work in college. You are the famous hipster if you have some ability. You would probably be an inspiration for your juniors.